Description
The Nexera UC (Unified Chromatography) is the world’s first fully automated system that combines on-line SFE and SFC in a single flow path. This unique system enables automatic extraction of up to 48 samples followed by seamless transfer to SFC/MS for high-sensitivity detection of targets by mass spectrometry. The automated extraction and chromatographic analysis is achieved using a mobile phase of supercritical carbon dioxide, which exhibits liquid-like dissolving power and diffusivity similar to gases, into which alcohol and other organic solvents are added as needed.
Features:- Eliminates the need for complicated sample preparation
- Enables highly reliable and stable analysis of delicate samples that are prone to oxidation or degradation if exposed to air and/or light
- Fully automated system has a much higher target analyte recovery rate and reduces the possibility of human error during analysis when compared to conventional manual workflows and off-line systems
- Wide range of separation modes
- Enables the analysis of compounds over a diverse chemical space
- Environmentally “green” instrument significantly reduces the quantity of organic solvents used
Multiple configurations are available -
- On-line SFE-SFC-MS system in which samples are extracted under light-shielding and anaerobic conditions in order to protect labile analytes from degradation
- Ultrafast SFC-MS/MS system for high-sensitivity analyses of compounds containing many analogues
- Automated high-speed chiral screening system
- SFC-UV system
The Nexera UC system is designed to fulfil the measurement requirements of a wide range of applications -
- Monitoring pesticides in food products
- Searching for disease biomarkers
- Drug discovery research in pharmaceuticals
- Cleaning validation
- Analyzing additives in polymer samples